EDUCATION
Aug. 2007 – May. 2012
Ph.D. in Biomedical Engineering
Weldon School of Purdue University, USA
Sep. 2004 – Aug. 2006
M.S. in Graduate School of Biomedical Engineering Yonsei University, Korea
KIST-Academia Collaborative Education Program Korea Institute of Science and Technology, Korea
Mar. 1998 – Feb. 2002
B.S. in Biomedical Engineering
Yonsei University, Korea
WORK EXPERIENCE
May. 2012 – Present
Post-doctoral Fellow
Houston Methodist Research Institute, TX, USA
- Development of discoidal nanoconstructs for MRI/Optical/PET multimodality imaging and combinatorial therapy using top-down fabrication strategy
- Development of hybrid nanoparticles for PET/MRI dual-modality imaging and therapy
- Development of red blood cell based transporter for multimodality imaging
Aug. 2007 – May. 2012
Graduate Research Assistant (Doctoral Degree)
Biomedical Engineering Department, Purdue University, IN, USA
- Development of MRI/Optical multimodality nanoparticles
Jul. 2004 – Jun. 2007
Student Researcher in Biomedical Research Center
Korea Institute of Science and Technology, Seoul, Korea
- Development of image-guided surgery system
- Development of early diagnosis system of inflammation disease and osteoarthritis
Sep. 2004 – Aug. 2006
Graduate Research Assistant (Master Degree) Yonsei University, Seoul, Korea
- Development of the web-based 2D/3D image processing and remote control of medical images
Mar. 2002 – Jun. 2004
The Korean Armed Forces 11th Artillery Division, Hongchun, Korea
- Observer officer as a second lieutenant
- Intelligence officer and fire support officer as a first lieutenant
RESEARCH INTERESTS
- Precise fabrication of homogeneous nanoconstructs with a customized shape
- Organic and inorganic nanoparticles for multimodality imaging and drug delivery system
- 2D/3D medical image processing and registration techniques for image-guided surgery
SPECIALTIES
Synthesis and fabrication of nanoconstructs: contrast agents, drug delivery systems, nanotechnology, polymeric materials, multi-modality imaging, Particle characterization: SEM, TEM, AFM, ICP-OES, ICP-MS, relaxometer, DLS, Z-potential, HPLC, UV-Vis spectrophotometer, electrophoresis, MALDI-TOF, Cell experiments: 2D/3D cell culture, cell uptake tests, cytotoxicity test, Laser Enabled Analysis and Processing (LEAPTM), confocal microscopy, Mice experiments: xenograft of malignant tumor, injection skills (intraperitoneal, subcutaneous, intradermal, tail-vein), anesthesia, euthanasia, autopsy, operation of various imaging modalities (eXplore Optix System, IVIS, Cri-Maestro, 3 Tesla GE and Philips MRI, Inveon PET-SPECT-CT), Computer coding of Labview, Matlab, Visual C++, and MFC
PUBLICATIONS
Ph.D. Dissertation in 2012
DESIGN OF MAGNETIC AND FLUORESCENT NANOPARTICLES FOR IN VIVO MR AND NIRF CANCER IMAGING
M.S. Thesis in 2006
STUDY OF REGION-BASED 3D IMAGE REGISTRATION TECHNIQUE IN TKR OPERATION
Journal Papers (published)
1.“Nanoparticles for Multimodality In Vivo Imaging in Nanomedicine, International Journal of Nanomedicine, 2013 (in press)
2.“Engineering Discoidal Polymeric Nanoconstructs with Enhanced Magneto-Optical Properties for Tumor Imaging”, Biomaterials, 34(21):5402-10, 2013
3.“Engineered Magnetic Hybrid Nanoparticles with Enhanced Relaxivity for Tumor Imaging”, Biomaterials, 34(31):7725-322013, 2013
4.“In vivo NIRF and MR dual-modality imaging using glycol chitosan nanoparticles”, Journal of Controlled Drug Release, 163:249-55, 2012
5.“3D Visualization for Tele-Medical Diagnosis”, Lecture Notes in Computer Science, vol.3980, 2006.
6.“Region-based 3D Image Registration Technique for TKR”, Journal of Biomedical Engineering Research, 390-400, 2006.
7.“Web-Based Hybrid Visualization of Medical Images”, Lecture Notes in Computer Science, vol.3568, 2005.
8.“Performance Test of Web Based 3D Medical Image System using Image Streaming Technique”, The Korea Society of Medical Informatics, Vol.11(4), 2005.
Journal Papers (in process)
9.“Hierarchically-structured magnetic nanoconstructs with enhanced relaxivity and tumor targeting capability”, Nature Communications, 2013 (in revision)
10.”Engineering Multimodal Chitosan Nanoparticles for Bladder Cancer Imaging”, Small, 2013 (in revision)
11.“Positron Emitting Magnetic Nanoconstructs for Hybrid PET/MR Imaging of Solid Tumors”, Journal of Nuclear Medicine, 2013 (in revision), § co-first authors
12.“MRI and NIRF imaging of murine bladder tumor using chitosan based nanocarriers for MRI based cancer detection and NIRF imaging guided cancer removal, Molecular Cancer, 2013 (in submission)
13.“Observation of theranostic window using hydrotropic micelle”, 2013 (in writing)
Conference Papers
1.“Theranostic PLGA/PEG Discoidal Polymeric Nanoconstructs”, CRS, 2013, Hawaii, USA
2.“Human organ-on-a-chip BioMEMS devices for testing new diagnostic and therapeutic strategies”, Proc. SPIE vol. 8615, 86150A, 2013, USA
3.“Multimodal in-vivo MRI and NIRF imaging of bladder tumor using peptide conjugated glycol chitosan nanoparticles”, Proc. of SPIE, 2012, USA
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